Steve, Dan, and Holly discuss the background and use of Ketamine in EMS. The trio interviews their guest, Oregon Firefighter/Paramedic Isaiah Burkhart, an Army Ranger veteran, about his experience with Ketamine personally and professionally. Various calls are discussed outlining what went well and what could have gone better when it comes to chemical restraint. Various doses and indications for the drug are discussed along with what the future of Ketamine use could look like in depression and psychotherapy treatment modalities.